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AffyRNADegradation: control and correction of RNA quality effects in GeneChip expression data

Motivation: Gene expression experiments aim to accurately quantify thousands of transcripts in parallel. Factors posterior to RNA extraction can, however, impair their accurate representation. RNA degradation and differences in the efficiency of amplification affect raw intensity measurements using...

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Detalles Bibliográficos
Autores principales: Fasold, Mario, Binder, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530908/
https://www.ncbi.nlm.nih.gov/pubmed/23097420
http://dx.doi.org/10.1093/bioinformatics/bts629