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Proliferation of Genetically Modified Human Cells on Electrospun Nanofiber Scaffolds
Gene editing is a process by which single base mutations can be corrected, in the context of the chromosome, using single-stranded oligodeoxynucleotides (ssODNs). The survival and proliferation of the corrected cells bearing modified genes, however, are impeded by a phenomenon known as reduced proli...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530926/ https://www.ncbi.nlm.nih.gov/pubmed/23212298 http://dx.doi.org/10.1038/mtna.2012.51 |