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Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. With ~170 million individuals infected and current interferon-based treatment having toxic side-effects and marginal efficacy, more effective antivirals are critically needed(1). Although HCV protease inhibitors were just FDA app...

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Detalles Bibliográficos
Autores principales: Sainz, Bruno, Barretto, Naina, Martin, Danyelle N., Hiraga, Nobuhiko, Imamura, Michio, Hussain, Snawar, Marsh, Katherine A., Yu, Xuemei, Chayama, Kazuaki, Alrefai, Waddah A., Uprichard, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530957/
https://www.ncbi.nlm.nih.gov/pubmed/22231557
http://dx.doi.org/10.1038/nm.2581