KIDFamMap: a database of kinase-inhibitor-disease family maps for kinase inhibitor selectivity and binding mechanisms

Kinases play central roles in signaling pathways and are promising therapeutic targets for many diseases. Designing selective kinase inhibitors is an emergent and challenging task, because kinases share an evolutionary conserved ATP-binding site. KIDFamMap (http://gemdock.life.nctu.edu.tw/KIDFamMap/...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Yuan, Lin, Chih-Ta, Huang, Jhang-Wei, Hsu, Kai-Cheng, Tseng, Jen-Hu, You, Syuan-Ren, Yang, Jinn-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531076/
https://www.ncbi.nlm.nih.gov/pubmed/23193279
http://dx.doi.org/10.1093/nar/gks1218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531076/
https://www.ncbi.nlm.nih.gov/pubmed/23193279
http://dx.doi.org/10.1093/nar/gks1218

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