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New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

CATH version 3.5 (Class, Architecture, Topology, Homology, available at http://www.cathdb.info/) contains 173 536 domains, 2626 homologous superfamilies and 1313 fold groups. When focusing on structural genomics (SG) structures, we observe that the number of new folds for CATH v3.5 is slightly less...

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Detalles Bibliográficos
Autores principales: Sillitoe, Ian, Cuff, Alison L., Dessailly, Benoit H., Dawson, Natalie L., Furnham, Nicholas, Lee, David, Lees, Jonathan G., Lewis, Tony E., Studer, Romain A., Rentzsch, Robert, Yeats, Corin, Thornton, Janet M., Orengo, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531114/
https://www.ncbi.nlm.nih.gov/pubmed/23203873
http://dx.doi.org/10.1093/nar/gks1211