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SwissBioisostere: a database of molecular replacements for ligand design

The SwissBioisostere database (http://www.swissbioisostere.ch) contains information on molecular replacements and their performance in biochemical assays. It is meant to provide researchers in drug discovery projects with ideas for bioisosteric modifications of their current lead molecule, as well a...

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Detalles Bibliográficos
Autores principales: Wirth, Matthias, Zoete, Vincent, Michielin, Olivier, Sauer, Wolfgang H. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531158/
https://www.ncbi.nlm.nih.gov/pubmed/23161688
http://dx.doi.org/10.1093/nar/gks1059