A Statistical Interaction between Circumsporozoite Protein-Specific T Cell and Antibody Responses and Risk of Clinical Malaria Episodes following Vaccination with RTS,S/AS01E

The candidate malaria vaccine RTS,S/AS01(E) provides significant but partial protection from clinical malaria. On in vitro circumsporozoite protein (CSP) peptide stimulation and intra-cellular cytokine staining of whole blood taken from 407 5–17 month-old children in a phase IIb trial of RTS,S/AS01(...

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Detalles Bibliográficos
Autores principales: Ndungu, Francis M., Mwacharo, Jedidah, Kimani, Domtila, Kai, Oscar, Moris, Philippe, Jongert, Erik, Vekemans, Johan, Olotu, Ally, Bejon, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531328/
https://www.ncbi.nlm.nih.gov/pubmed/23300801
http://dx.doi.org/10.1371/journal.pone.0052870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531328/
https://www.ncbi.nlm.nih.gov/pubmed/23300801
http://dx.doi.org/10.1371/journal.pone.0052870

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