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The Role of Insulin C-Peptide in the Coevolution Analyses of the Insulin Signaling Pathway: A Hint for Its Functions

As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive...

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Detalles Bibliográficos
Autores principales: Wang, Shuai, Wei, Wei, Zheng, Yadong, Hou, Junling, Dou, Yongxi, Zhang, Shaohua, Luo, Xuenong, Cai, Xuepeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531361/
https://www.ncbi.nlm.nih.gov/pubmed/23300796
http://dx.doi.org/10.1371/journal.pone.0052847