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The Role of Insulin C-Peptide in the Coevolution Analyses of the Insulin Signaling Pathway: A Hint for Its Functions
As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive...
Autores principales: | Wang, Shuai, Wei, Wei, Zheng, Yadong, Hou, Junling, Dou, Yongxi, Zhang, Shaohua, Luo, Xuenong, Cai, Xuepeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531361/ https://www.ncbi.nlm.nih.gov/pubmed/23300796 http://dx.doi.org/10.1371/journal.pone.0052847 |
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