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Extended and Structurally Supported Insights into Extracellular Hormone Binding, Signal Transduction and Organization of the Thyrotropin Receptor

The hormone thyrotropin (TSH) and its receptor (TSHR) are crucial for the growth and function of the thyroid gland. The TSHR is evolutionary linked with the receptors of follitropin (FSHR) and lutropin/choriogonadotropin (LHR) and their sequences and structures are similar. The extracellular region...

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Detalles Bibliográficos
Autores principales: Krause, Gerd, Kreuchwig, Annika, Kleinau, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531376/
https://www.ncbi.nlm.nih.gov/pubmed/23300822
http://dx.doi.org/10.1371/journal.pone.0052920