Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts

Osterix (Osx) is an osteoblast-specific transcription factor required for osteoblast differentiation. Inhibition of Wnt pathway by Osx highlights the potential for feedback control mechanisms involved in bone formation. Hypoxia-inducible factor-1α (HIF-1α) is a master regulator of hypoxia. HIF-1α ha...

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Detalles Bibliográficos
Autores principales: Chen, Dafu, Li, Yang, Zhou, Zhiyu, Xing, Yonggang, Zhong, Yu, Zou, Xuenong, Tian, Wei, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531395/
https://www.ncbi.nlm.nih.gov/pubmed/23300831
http://dx.doi.org/10.1371/journal.pone.0052948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531395/
https://www.ncbi.nlm.nih.gov/pubmed/23300831
http://dx.doi.org/10.1371/journal.pone.0052948

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