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Combination Therapy Using Monoclonal Antibodies against Respiratory Syncytial Virus (RSV) G Glycoprotein Protects from RSV Disease in BALB/c Mice

Therapeutic options to control respiratory syncytial virus (RSV) are limited, thus development of new therapeutics is high priority. Previous studies with a monoclonal antibody (mAb) reactive to an epitope proximal to the central conserved region (CCR) of RSV G protein (mAb 131-2G) showed therapeuti...

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Detalles Bibliográficos
Autores principales: Caidi, Hayat, Harcourt, Jennifer L., Tripp, Ralph A., Anderson, Larry J., Haynes, Lia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531420/
https://www.ncbi.nlm.nih.gov/pubmed/23300550
http://dx.doi.org/10.1371/journal.pone.0051485