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Gene Expression Profile and Functionality of ESC-Derived Lin-ckit+Sca-1+ Cells Are Distinct from Lin-ckit+Sca-1+ Cells Isolated from Fetal Liver or Bone Marrow

In vitro bioreactor-based cultures are being extensively investigated for large-scale production of differentiated cells from embryonic stem cells (ESCs). However, it is unclear whether in vitro ESC-derived progenitors have similar gene expression profiles and functionalities as their in vivo counte...

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Detalles Bibliográficos
Autores principales: Fernandez, Irina, Fridley, Krista M., Arasappan, Dhivya, Ambler, Rosalind V., Tucker, Philip W., Roy, Krishnendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531429/
https://www.ncbi.nlm.nih.gov/pubmed/23300581
http://dx.doi.org/10.1371/journal.pone.0051944