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Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny

The development of a megakaryocyte lineage specific Cre deleter, using the Pf4 (CXCL4) promoter (Pf4-Cre), was a significant step forward in the specific analysis of platelet and megakaryocyte cell biology. However, in the present study we have employed a sensitive reporter-based approach to demonst...

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Detalles Bibliográficos
Autores principales: Calaminus, Simon D. J., Guitart, Amelie, Sinclair, Amy, Schachtner, Hannah, Watson, Steve P., Holyoake, Tessa L., Kranc, Kamil R., Machesky, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531453/
https://www.ncbi.nlm.nih.gov/pubmed/23300543
http://dx.doi.org/10.1371/journal.pone.0051361