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Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny
The development of a megakaryocyte lineage specific Cre deleter, using the Pf4 (CXCL4) promoter (Pf4-Cre), was a significant step forward in the specific analysis of platelet and megakaryocyte cell biology. However, in the present study we have employed a sensitive reporter-based approach to demonst...
Autores principales: | Calaminus, Simon D. J., Guitart, Amelie, Sinclair, Amy, Schachtner, Hannah, Watson, Steve P., Holyoake, Tessa L., Kranc, Kamil R., Machesky, Laura M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531453/ https://www.ncbi.nlm.nih.gov/pubmed/23300543 http://dx.doi.org/10.1371/journal.pone.0051361 |
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