Antigen Recognition By Autoreactive Cd4(+) Thymocytes Drives Homeostasis Of The Thymic Medulla

The thymic medulla is dedicated for purging the T-cell receptor (TCR) repertoire of self-reactive specificities. Medullary thymic epithelial cells (mTECs) play a pivotal role in this process because they express numerous peripheral tissue-restricted self-antigens. Although it is well known that medu...

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Detalles Bibliográficos
Autores principales: Irla, Magali, Guerri, Lucia, Guenot, Jeanne, Sergé, Arnauld, Lantz, Olivier, Liston, Adrian, Imhof, Beat A., Palmer, Ed, Reith, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531460/
https://www.ncbi.nlm.nih.gov/pubmed/23300712
http://dx.doi.org/10.1371/journal.pone.0052591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531460/
https://www.ncbi.nlm.nih.gov/pubmed/23300712
http://dx.doi.org/10.1371/journal.pone.0052591

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