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Excessive Astrocyte-Derived Neurotrophin-3 Contributes to the Abnormal Neuronal Dendritic Development in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is a form of inherited mental retardation in humans that results from expansion of a CGG repeat in the Fmr1 gene. Recent studies suggest a role of astrocytes in neuronal development. However, the mechanisms involved in the regulation process of astrocytes from FXS remain unc...

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Detalles Bibliográficos
Autores principales: Yang, Qi, Feng, Bin, Zhang, Kun, Guo, Yan-yan, Liu, Shui-bing, Wu, Yu-mei, Li, Xiao-qiang, Zhao, Ming-gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531466/
https://www.ncbi.nlm.nih.gov/pubmed/23300470
http://dx.doi.org/10.1371/journal.pgen.1003172