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Transgenerational Propagation and Quantitative Maintenance of Paternal Centromeres Depends on Cid/Cenp-A Presence in Drosophila Sperm

In Drosophila melanogaster, as in many animal and plant species, centromere identity is specified epigenetically. In proliferating cells, a centromere-specific histone H3 variant (CenH3), named Cid in Drosophila and Cenp-A in humans, is a crucial component of the epigenetic centromere mark. Hence, m...

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Detalles Bibliográficos
Autores principales: Raychaudhuri, Nitika, Dubruille, Raphaelle, Orsi, Guillermo A., Bagheri, Homayoun C., Loppin, Benjamin, Lehner, Christian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531477/
https://www.ncbi.nlm.nih.gov/pubmed/23300376
http://dx.doi.org/10.1371/journal.pbio.1001434