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Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV). HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order to counteract host cellular restriction fac...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531493/ https://www.ncbi.nlm.nih.gov/pubmed/23300442 http://dx.doi.org/10.1371/journal.ppat.1003085 |