Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV). HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order to counteract host cellular restriction fac...

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Detalles Bibliográficos
Autores principales: Stanley, David J., Bartholomeeusen, Koen, Crosby, David C., Kim, Dong Young, Kwon, Eunju, Yen, Linda, Cartozo, Nathalie Caretta, Li, Ming, Jäger, Stefanie, Mason-Herr, Jeremy, Hayashi, Fumiaki, Yokoyama, Shigeyuki, Krogan, Nevan J., Harris, Reuben S., Peterlin, Boris Matija, Gross, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531493/
https://www.ncbi.nlm.nih.gov/pubmed/23300442
http://dx.doi.org/10.1371/journal.ppat.1003085

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