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Components of Selection in the Evolution of the Influenza Virus: Linkage Effects Beat Inherent Selection

The influenza virus is an important human pathogen, with a rapid rate of evolution in the human population. The rate of homologous recombination within genes of influenza is essentially zero. As such, where two alleles within the same gene are in linkage disequilibrium, interference between alleles...

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Detalles Bibliográficos
Autores principales: Illingworth, Christopher J. R., Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531508/
https://www.ncbi.nlm.nih.gov/pubmed/23300444
http://dx.doi.org/10.1371/journal.ppat.1003091