Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons

The striking differences between the clinical symptoms of tetanus and botulism have been ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. Tetanus toxin (TeNT) is known to undergo transcytosis into inhibitory interneurons and block the release of inhibito...

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Detalles Bibliográficos
Autores principales: Restani, Laura, Giribaldi, Francesco, Manich, Maria, Bercsenyi, Kinga, Menendez, Guillermo, Rossetto, Ornella, Caleo, Matteo, Schiavo, Giampietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531519/
https://www.ncbi.nlm.nih.gov/pubmed/23300443
http://dx.doi.org/10.1371/journal.ppat.1003087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531519/
https://www.ncbi.nlm.nih.gov/pubmed/23300443
http://dx.doi.org/10.1371/journal.ppat.1003087

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