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Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons
The striking differences between the clinical symptoms of tetanus and botulism have been ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. Tetanus toxin (TeNT) is known to undergo transcytosis into inhibitory interneurons and block the release of inhibito...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531519/ https://www.ncbi.nlm.nih.gov/pubmed/23300443 http://dx.doi.org/10.1371/journal.ppat.1003087 |