Correcting pervasive errors in RNA crystallography through enumerative structure prediction

Three-dimensional RNA models fitted into crystallographic density maps exhibit pervasive conformational ambiguities, geometric errors, and steric clashes. To address these problems, we present Enumerative Real-space Refinement ASsisted by Electron density under Rosetta (ERRASER), coupled to PHENIX (...

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Detalles Bibliográficos
Autores principales: Chou, Fang-Chieh, Sripakdeevong, Parin, Dibrov, Sergey M., Hermann, Thomas, Das, Rhiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531565/
https://www.ncbi.nlm.nih.gov/pubmed/23202432
http://dx.doi.org/10.1038/nmeth.2262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531565/
https://www.ncbi.nlm.nih.gov/pubmed/23202432
http://dx.doi.org/10.1038/nmeth.2262

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