Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

The mechanisms behind flares of human autoimmune diseases in general, and of systemic lupus in particular, are poorly understood. The present scenario proposes that predisposing gene defects favour clinical flares under the influence of external stimuli. Here, we show that Carabin is low in B cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Schickel, Jean-Nicolas, Pasquali, Jean-Louis, Soley, Anne, Knapp, Anne-Marie, Decossas, Marion, Kern, Aurélie, Fauny, Jean-Daniel, Marcellin, Luc, Korganow, Anne-Sophie, Martin, Thierry, Soulas-Sprauel, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531602/
https://www.ncbi.nlm.nih.gov/pubmed/23109291
http://dx.doi.org/10.1002/emmm.201201595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531602/
https://www.ncbi.nlm.nih.gov/pubmed/23109291
http://dx.doi.org/10.1002/emmm.201201595

Ejemplares similares