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Phosphorylation as a Tool To Modulate Aggregation Propensity and To Predict Fibril Architecture

ABSTRACT: Despite the importance of post-translational modifications in controlling the solubility and conformational properties of proteins and peptides, precisely how the aggregation propensity of different peptide sequences is modulated by chemical modification remains unclear. Here we have inves...

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Detalles Bibliográficos
Autores principales: Valette, Nathalie M, Radford, Sheena E, Harris, Sarah A, Warriner, Stuart L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531611/
https://www.ncbi.nlm.nih.gov/pubmed/22174034
http://dx.doi.org/10.1002/cbic.201100607