Automated cleaning and pre-processing of immunoglobulin gene sequences from high-throughput sequencing

High-throughput sequencing (HTS) yields tens of thousands to millions of sequences that require a large amount of pre-processing work to clean various artifacts. Such cleaning cannot be performed manually. Existing programs are not suitable for immunoglobulin (Ig) genes, which are variable and often...

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Detalles Bibliográficos
Autores principales: Michaeli, Miri, Noga, Hila, Tabibian-Keissar, Hilla, Barshack, Iris, Mehr, Ramit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531709/
https://www.ncbi.nlm.nih.gov/pubmed/23293637
http://dx.doi.org/10.3389/fimmu.2012.00386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531709/
https://www.ncbi.nlm.nih.gov/pubmed/23293637
http://dx.doi.org/10.3389/fimmu.2012.00386

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