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Automated cleaning and pre-processing of immunoglobulin gene sequences from high-throughput sequencing
High-throughput sequencing (HTS) yields tens of thousands to millions of sequences that require a large amount of pre-processing work to clean various artifacts. Such cleaning cannot be performed manually. Existing programs are not suitable for immunoglobulin (Ig) genes, which are variable and often...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531709/ https://www.ncbi.nlm.nih.gov/pubmed/23293637 http://dx.doi.org/10.3389/fimmu.2012.00386 |