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In Vivo Phosphorylation of Ser(21) and Ser(83) during Nutrient-induced Activation of the Yeast Protein Kinase A (PKA) Target Trehalase

The readdition of an essential nutrient to starved, fermenting cells of the yeast Saccharomyces cerevisiae triggers rapid activation of the protein kinase A (PKA) pathway. Trehalase is activated 5–10-fold within minutes and has been used as a convenient reporter for rapid activation of PKA in vivo....

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Detalles Bibliográficos
Autores principales: Schepers, Wim, Van Zeebroeck, Griet, Pinkse, Martijn, Verhaert, Peter, Thevelein, Johan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531729/
https://www.ncbi.nlm.nih.gov/pubmed/23155055
http://dx.doi.org/10.1074/jbc.M112.421503