Cargando…

In Vivo Phosphorylation of Ser(21) and Ser(83) during Nutrient-induced Activation of the Yeast Protein Kinase A (PKA) Target Trehalase

The readdition of an essential nutrient to starved, fermenting cells of the yeast Saccharomyces cerevisiae triggers rapid activation of the protein kinase A (PKA) pathway. Trehalase is activated 5–10-fold within minutes and has been used as a convenient reporter for rapid activation of PKA in vivo....

Descripción completa

Detalles Bibliográficos
Autores principales:	Schepers, Wim, Van Zeebroeck, Griet, Pinkse, Martijn, Verhaert, Peter, Thevelein, Johan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531729/ https://www.ncbi.nlm.nih.gov/pubmed/23155055 http://dx.doi.org/10.1074/jbc.M112.421503

Ejemplares similares

Phosphorylation of Rat Melanopsin at Ser-381 and Ser-398 by Light/Dark and Its Importance for Intrinsically Photosensitive Ganglion Cells (ipRGCs) Cellular Ca(2+) Signaling
por: Fahrenkrug, Jan, et al.
Publicado: (2014)

Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells
por: Haushalter, Kristofer J., et al.
Publicado: (2018)

Protein Phosphatase 1-α Regulates AS160 Ser(588) and Thr(642) Dephosphorylation in Skeletal Muscle
por: Sharma, Pragya, et al.
Publicado: (2016)

Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity
por: Burmeister, Brian T., et al.
Publicado: (2015)

The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho–Ser-621 in the C terminus of CRAF
por: Yuan, Jimin, et al.
Publicado: (2018)

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
por: Morino, Katsutaro, et al.
Publicado: (2008)

Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca(2+) sensitivity and calpain-induced proteolysis
por: Martin-Garrido, Abel, et al.
Publicado: (2018)

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes
por: Christian, Frank, et al.
Publicado: (2011)

Acute Stimulation of White Adipocyte Respiration by PKA-Induced Lipolysis
por: Yehuda-Shnaidman, Einav, et al.
Publicado: (2010)

Cdk5-mediated Phosphorylation of c-Myc on Ser-62 Is Essential in Transcriptional Activation of Cyclin B1 by Cyclin G1
por: Seo, Haeng Ran, et al.
Publicado: (2008)

Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites
por: Nirujogi, Raja S., et al.
Publicado: (2021)

Engineering A-kinase Anchoring Protein (AKAP)-selective Regulatory Subunits of Protein Kinase A (PKA) through Structure-based Phage Selection
por: Gold, Matthew G., et al.
Publicado: (2013)

Sul1 and Sul2 Sulfate Transceptors Signal to Protein Kinase A upon Exit of Sulfur Starvation
por: Kankipati, Harish Nag, et al.
Publicado: (2015)

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)
por: Keshwani, Malik M., et al.
Publicado: (2011)

Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA
por: Van Zeebroeck, Griet, et al.
Publicado: (2020)

MYPT1 Protein Isoforms Are Differentially Phosphorylated by Protein Kinase G
por: Yuen, Samantha, et al.
Publicado: (2011)

The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation
por: Eklund, Greta, et al.
Publicado: (2014)

Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-β Production
por: Nistal-Villán, Estanislao, et al.
Publicado: (2010)

Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code
por: Butcher, Adrian J., et al.
Publicado: (2011)

Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes
por: Mashili, Fredirick, et al.
Publicado: (2013)

Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
por: Tang, Liu-Ya, et al.
Publicado: (2021)

Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes
por: Roberts, David J., et al.
Publicado: (2013)

Capillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain Tissue
por: Schrötter, Sandra, et al.
Publicado: (2016)

A New Pathway of CD5 Glycoprotein-mediated T Cell Inhibition Dependent on Inhibitory Phosphorylation of Fyn Kinase
por: Bamberger, Martina, et al.
Publicado: (2011)

Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders
por: Li, Min, et al.
Publicado: (2015)

Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis
por: Kuo, Taiyi, et al.
Publicado: (2017)

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING
por: Séverin, Sonia, et al.
Publicado: (2011)

Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5
por: Bernatík, Ondřej, et al.
Publicado: (2014)

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4
por: Butcher, Adrian J., et al.
Publicado: (2014)

p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration
por: Samson, Shiela C., et al.
Publicado: (2019)

Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)(536) Phosphorylation
por: Zhao, Yanhua, et al.
Publicado: (2011)

Target of rapamycin complex 2–dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae
por: Bourgoint, Clélia, et al.
Publicado: (2018)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

Multiple Transceptors for Macro- and Micro-Nutrients Control Diverse Cellular Properties Through the PKA Pathway in Yeast: A Paradigm for the Rapidly Expanding World of Eukaryotic Nutrient Transceptors Up to Those in Human Cells
por: Steyfkens, Fenella, et al.
Publicado: (2018)

mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets
por: Moore, Samantha F., et al.
Publicado: (2011)

Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2: INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS
por: Beautrait, Alexandre, et al.
Publicado: (2014)

Activated Cdc42-associated kinase 1 (ACK1) binds the sterile α motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines
por: Thaker, Youg R., et al.
Publicado: (2017)

Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDIα) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion
por: Dovas, Athanassios, et al.
Publicado: (2010)

Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways
por: Dickinson, Robin J., et al.
Publicado: (2011)

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity
por: Sajan, Mini P., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vfd8gpqkmb76vu22s32m9g630s