Differential Arabinan Capping of Lipoarabinomannan Modulates Innate Immune Responses and Impacts T Helper Cell Differentiation

Toll-like receptors (TLRs) recognize pathogens by interacting with pathogen-associated molecular patterns, such as the phosphatidylinositol-based lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM). Such structures are present in several pathogens, including Mycobacterium tuberculosis, being im...

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Detalles Bibliográficos
Autores principales: Mishra, Arun K., Alves, Joana E., Krumbach, Karin, Nigou, Jerome, Castro, António G., Geurtsen, Jeroen, Eggeling, Lothar, Saraiva, Margarida, Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531733/
https://www.ncbi.nlm.nih.gov/pubmed/23144457
http://dx.doi.org/10.1074/jbc.M112.402396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531733/
https://www.ncbi.nlm.nih.gov/pubmed/23144457
http://dx.doi.org/10.1074/jbc.M112.402396

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