Cargando…
Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently-marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di- and tri-substituted pyridines in an efficien...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531798/ https://www.ncbi.nlm.nih.gov/pubmed/23247178 http://dx.doi.org/10.1038/nchem.1504 |