Phosphorylation-enabled binding of Sgo1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis

Timely dissolution of sister-chromatid cohesion in mitosis ensures accurate chromosome segregation to guard against aneuploidy and tumorigenesis. The complex of shugoshin and protein phosphatase 2A (Sgo1–PP2A) protects cohesin at centromeres from premature removal by mitotic kinases and Wapl in prop...

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Detalles Bibliográficos
Autores principales: Liu, Hong, Rankin, Susannah, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531828/
https://www.ncbi.nlm.nih.gov/pubmed/23242214
http://dx.doi.org/10.1038/ncb2637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531828/
https://www.ncbi.nlm.nih.gov/pubmed/23242214
http://dx.doi.org/10.1038/ncb2637

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