Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast

The high osmolarity glycerol (HOG) pathway in yeast serves as a prototype signalling system for eukaryotes. We used an unprecedented amount of data to parameterise 192 models capturing different hypotheses about molecular mechanisms underlying osmo-adaptation and selected a best approximating model....

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Detalles Bibliográficos
Autores principales: Schaber, Jörg, Baltanas, Rodrigo, Bush, Alan, Klipp, Edda, Colman-Lerner, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531907/
https://www.ncbi.nlm.nih.gov/pubmed/23149687
http://dx.doi.org/10.1038/msb.2012.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531907/
https://www.ncbi.nlm.nih.gov/pubmed/23149687
http://dx.doi.org/10.1038/msb.2012.53

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