Cargando…
Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast
The high osmolarity glycerol (HOG) pathway in yeast serves as a prototype signalling system for eukaryotes. We used an unprecedented amount of data to parameterise 192 models capturing different hypotheses about molecular mechanisms underlying osmo-adaptation and selected a best approximating model....
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531907/ https://www.ncbi.nlm.nih.gov/pubmed/23149687 http://dx.doi.org/10.1038/msb.2012.53 |