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PEP-1-CAT-Transduced Mesenchymal Stem Cells Acquire an Enhanced Viability and Promote Ischemia-Induced Angiogenesis

OBJECTIVE: Poor survival of mesenchymal stem cells (MSC) compromised the efficacy of stem cell therapy for ischemic diseases. The aim of this study is to investigate the role of PEP-1-CAT transduction in MSC survival and its effect on ischemia-induced angiogenesis. METHODS: MSC apoptosis was evaluat...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Dong, Xiao-Wei, Wang, Jia-Ning, Tang, Jun-Ming, Yang, Jian-Ye, Guo, Ling-Yun, Zheng, Fei, Kong, Xia, Huang, Yong-Zhang, Chen, Shi-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532064/
https://www.ncbi.nlm.nih.gov/pubmed/23285080
http://dx.doi.org/10.1371/journal.pone.0052537