Pharmacological Inhibition of Caspase-2 Protects Axotomised Retinal Ganglion Cells from Apoptosis in Adult Rats

Severing the axons of retinal ganglion cells (RGC) by crushing the optic nerve (ONC) causes the majority of RGC to degenerate and die, primarily by apoptosis. We showed recently that after ONC in adult rats, caspase-2 activation occurred specifically in RGC while no localisation of caspase-3 was obs...

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Detalles Bibliográficos
Autores principales: Vigneswara, Vasanthy, Berry, Martin, Logan, Ann, Ahmed, Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532067/
https://www.ncbi.nlm.nih.gov/pubmed/23285297
http://dx.doi.org/10.1371/journal.pone.0053473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532067/
https://www.ncbi.nlm.nih.gov/pubmed/23285297
http://dx.doi.org/10.1371/journal.pone.0053473

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