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Mutual information and variants for protein domain-domain contact prediction

BACKGROUND: Predicting protein contacts solely based on sequence information remains a challenging problem, despite the huge amount of sequence data at our disposal. Mutual Information (MI), an information theory measure, has been extensively employed and modified to identify residues within a prote...

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Detalles Bibliográficos
Autores principales: Gomes, Mireille, Hamer, Rebecca, Reinert, Gesine, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532072/
https://www.ncbi.nlm.nih.gov/pubmed/23244412
http://dx.doi.org/10.1186/1756-0500-5-472