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IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation

BACKGROUND: IL-1β is a pleiotropic pro-inflammatory cytokine and its up-regulation is closely associated with various cancers including gastrointestinal tumors. However, it remains unclear how IL-1β may contribute to the initiation and development of these inflammation-associated cancers. Here we in...

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Detalles Bibliográficos
Autores principales: Li, Yijing, Wang, Lei, Pappan, Loretta, Galliher-Beckley, Amy, Shi, Jishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532073/
https://www.ncbi.nlm.nih.gov/pubmed/23174018
http://dx.doi.org/10.1186/1476-4598-11-87