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Oscillations in MAPK cascade triggered by two distinct designs of coupled positive and negative feedback loops
BACKGROUND: Feedback loops, both positive and negative are embedded in the Mitogen Activated Protein Kinase (MAPK) cascade. In the three layer MAPK cascade, both feedback loops originate from the terminal layer and their sites of action are either of the two upstream layers. Recent studies have show...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532088/ https://www.ncbi.nlm.nih.gov/pubmed/22694947 http://dx.doi.org/10.1186/1756-0500-5-287 |