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Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease

OBJECTIVES: Accumulating evidence suggested that dysregulation of cholesterol homeostasis might be a major etiologic factor in initiating and promoting neurodegeneration in Alzheimer’s disease (AD). ATP-binding cassette transporter A1 (ABCA1), hepatic lipase (HL, coding genes named LIPC) and cholest...

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Detalles Bibliográficos
Autores principales: Xiao, Zhijie, Wang, Juan, Chen, Weirong, Wang, Peng, Zeng, Houlin, Chen, Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532092/
https://www.ncbi.nlm.nih.gov/pubmed/23181436
http://dx.doi.org/10.1186/1476-511X-11-163