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A Novel Muscarinic Antagonist R2HBJJ Inhibits Non-Small Cell Lung Cancer Cell Growth and Arrests the Cell Cycle in G0/G1

Lung cancers express the cholinergic autocrine loop, which facilitates the progression of cancer cells. The antagonists of mAChRs have been demonstrated to depress the growth of small cell lung cancers (SCLCs). In this study we intended to investigate the growth inhibitory effect of R2HBJJ, a novel...

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Detalles Bibliográficos
Autores principales: Hua, Nan, Wei, Xiaoli, Liu, Xiaoyan, Ma, Xiaoyun, He, Xinhua, Zhuo, Rengong, Zhao, Zhe, Wang, Liyun, Yan, Haitao, Zhong, Bohua, Zheng, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532118/
https://www.ncbi.nlm.nih.gov/pubmed/23285263
http://dx.doi.org/10.1371/journal.pone.0053170