The effect of strand bias in Illumina short-read sequencing data

BACKGROUND: When using Illumina high throughput short read data, sometimes the genotype inferred from the positive strand and negative strand are significantly different, with one homozygous and the other heterozygous. This phenomenon is known as strand bias. In this study, we used Illumina short-re...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Li, Jiang, Li, Chung-I, Long, Jirong, Samuels, David C, Shyr, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532123/
https://www.ncbi.nlm.nih.gov/pubmed/23176052
http://dx.doi.org/10.1186/1471-2164-13-666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532123/
https://www.ncbi.nlm.nih.gov/pubmed/23176052
http://dx.doi.org/10.1186/1471-2164-13-666

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