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The effect of strand bias in Illumina short-read sequencing data
BACKGROUND: When using Illumina high throughput short read data, sometimes the genotype inferred from the positive strand and negative strand are significantly different, with one homozygous and the other heterozygous. This phenomenon is known as strand bias. In this study, we used Illumina short-re...
Autores principales: | Guo, Yan, Li, Jiang, Li, Chung-I, Long, Jirong, Samuels, David C, Shyr, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532123/ https://www.ncbi.nlm.nih.gov/pubmed/23176052 http://dx.doi.org/10.1186/1471-2164-13-666 |
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