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Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis

BACKGROUND: Human ß-defensins are a family of antimicrobial peptides located at the mucosal surface. Both sequence multi-site variations (MSV) and copy-number variants (CNV) of the defensin-encoding genes are associated with increased risk for various diseases, including cancer and inflammatory cond...

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Detalles Bibliográficos
Autores principales: Taudien, Stefan, Gäbel, Gabor, Kuss, Oliver, Groth, Marco, Grützmann, Robert, Huse, Klaus, Kluttig, Alexander, Wolf, Andreas, Nothnagel, Michael, Rosenstiel, Philip, Greiser, Karin Halina, Werdan, Karl, Krawczak, Michael, Pilarsky, Christian, Platzer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532138/
https://www.ncbi.nlm.nih.gov/pubmed/23148552
http://dx.doi.org/10.1186/1756-0500-5-629