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First Discovery and Stucture-Activity Relationship Study of Phenanthroquinolizidines as Novel Antiviral Agents against Tobacco Mosaic Virus (TMV)

A series of phenanthroquinolizidine alkaloids 1–24 were prepared and first evaluated for their antiviral activity against tobacco mosaic virus (TMV). The bioassay results showed that most of these compounds exhibited good to excellent in vivo anti-TMV activity, of which compounds 1, 2, 15 and 16 dis...

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Detalles Bibliográficos
Autores principales: Wang, Ziwen, Feng, Anzheng, Cui, Mingbo, Liu, Yuxiu, Wang, Lizhong, Wang, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532156/
https://www.ncbi.nlm.nih.gov/pubmed/23285230
http://dx.doi.org/10.1371/journal.pone.0052933