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Computational modeling of apoptotic signaling pathways induced by cisplatin

BACKGROUND: Apoptosis is an essential property of all higher organisms that involves extremely complex signaling pathways. Mathematical modeling provides a rigorous integrative approach for analyzing and understanding such intricate biological systems. RESULTS: Here, we constructed a large-scale, li...

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Detalles Bibliográficos
Autores principales: Hong, Ji-Young, Kim, Geun-Hong, Kim, Jun-Woo, Kwon, Soon-Sung, Sato, Eisuke F, Cho, Kwang-Hyun, Shim, Eun Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532179/
https://www.ncbi.nlm.nih.gov/pubmed/22967854
http://dx.doi.org/10.1186/1752-0509-6-122