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Cell Surface Concentrations and Concentration Ranges for Testing In Vitro Autocrine Loops and Small Molecules
A common assumption made when performing in vitro cellular assays is that the concentration of substances in the culture system is uniform. However, since the cells that internalize and secrete substances reside at the bottom of the well, it is conceivable that a concentration gradient could arise a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532204/ https://www.ncbi.nlm.nih.gov/pubmed/23284769 http://dx.doi.org/10.1371/journal.pone.0051796 |