Glucose-Induced Down Regulation of Thiamine Transporters in the Kidney Proximal Tubular Epithelium Produces Thiamine Insufficiency in Diabetes

Increased renal clearance of thiamine (vitamin B(1)) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy. We studied the mechanism of impaired renal re-uptake of thiamine in diabete...

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Detalles Bibliográficos
Autores principales: Larkin, James R., Zhang, Fang, Godfrey, Lisa, Molostvov, Guerman, Zehnder, Daniel, Rabbani, Naila, Thornalley, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532206/
https://www.ncbi.nlm.nih.gov/pubmed/23285265
http://dx.doi.org/10.1371/journal.pone.0053175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532206/
https://www.ncbi.nlm.nih.gov/pubmed/23285265
http://dx.doi.org/10.1371/journal.pone.0053175

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