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Functional Comparison of Chronological and In Vitro Aging: Differential Role of the Cytoskeleton and Mitochondria in Mesenchymal Stromal Cells

Mesenchymal stromal cells (MSCs) are of high relevance for the regeneration of mesenchymal tissues such as bone and cartilage. The promising role of MSCs in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age, t...

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Detalles Bibliográficos
Autores principales: Geißler, Sven, Textor, Martin, Kühnisch, Jirko, Könnig, Delia, Klein, Oliver, Ode, Andrea, Pfitzner, Tilman, Adjaye, James, Kasper, Grit, Duda, Georg N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532360/
https://www.ncbi.nlm.nih.gov/pubmed/23285157
http://dx.doi.org/10.1371/journal.pone.0052700